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Pathways Recommended:	Stem Cell/Wnt Cell Cycle/DNA Damage

Results for "

cord blood cells

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Endogenous Metabolite (1) Formyl Peptide Receptor (FPR) (1) Histone Methyltransferase (1) Reactive Oxygen Species (1)
By Research Areas:	Cancer (1) Cardiovascular Disease (1) Endocrinology (1) Infection (1) Inflammation/Immunology (1) Neurological Disease (1)

5

Inhibitors & Agonists

1

Peptides

1

MCE Kits

1

Natural
Products

Targets Recommended: Nuclear Factor of activated T Cells (NFAT)

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

Prostaglandin B2	Endogenous Metabolite	Cardiovascular Disease Endocrinology
Prostaglandin B2 is a prostaglandin. Prostaglandin B2 is the main substance in cord blood mesenchymal stem cells, to inhibit DC-T Cell proliferation. Prostaglandin B2 also induces cutaneous vasoconstriction of the canine hind paw .

XJB-5-131 2 Publications Verification	Reactive Oxygen Species	Neurological Disease
XJB-5-131 is a mitochondria-targeted ROS and electron scavenger . XJB-5-131 is a bi-functional antioxidant that comprises a radical scavenger. XJB-5-131 is a synthetic antioxidant that targets mitochondria . XJB-5-131 is an effective ionizing irradiation protector and mitigator of cord blood mononuclear cells (CB MNCs) .

Cyclosporin H 1 Publications Verification	Formyl Peptide Receptor (FPR)	Infection Inflammation/Immunology
Cyclosporin H is a selective and potent inhibitor of FPR-1 (formyl peptide receptor 1). Cyclosporin H, a viral transduction enhancer, increases lentiviral transduction up to 10-fold in human cord blood-derived hematopoietic stem and progenitor cells (HSPCs). Cyclosporin H displays an additive effect when combined with Rapamycin (HY-10219) or Prostaglandin E2 (HY-101952). Cyclosporin H lacks immunosuppressant activity of Cyclosporin A.

SGC0946 Maximum Cited Publications 7 Publications Verification	Histone Methyltransferase	Cancer
SGC0946 is a selective DOT1LH3K79 methyltransferase) inhibitor, with an IC₅₀ of 0.3 nM. SGC0946 results in G1 arrest, inhibits potential of cell self-renewal and metastatic, also induces cell differentiation. SGC0946 can be used in studies of leukemia and solid tumors and also serve as a probe to further investigate the cellular mechanism of DOT1L in both normal and diseased cells .

3-Deoxy-D-glycero-D-galacto-2-nonulosonic acid KDN	Others	Others
3-Deoxy-D-glycero-D-galacto-2-nonulosonic acid (KDN) is a sialic acid. 3-Deoxy-D-glycero-D-galacto-2-nonulosonic acid protects the oligo/(poly)sialyl chains from exosialidases at nonreducing terminal, and plays a role in egg activation of salmonid fish . 3-Deoxy-D-glycero-D-galacto-2-nonulosonic acid is abundant in fetal cord red blood cells and malignant human ovarian cancer cells .

Cat. No.	Product Name

Human CD34+ Cells Negative Selection Kit
MCE Human CD34⁺ Cells Negative Selection Kit is designed for the isolation of CD34⁺ cells from human cord blood mononuclear cells (CBMC) or human peripheral blood mononuclear cells (PBMC).

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